GRANULOCYTIC ANAPLASMOSIS IN CATS FROM CENTRAL EUROPE AND MOLECULAR CHARACTERIZATION OF FELINE ANAPLASMA PHAGOCYTOPHILUM STRAINS BY ANKA GENE, GROEL GENE AND MULTILOCUS SEQUENCE TYPING

Granulocytic anaplasmosis in cats from central Europe and molecular characterization of feline Anaplasma phagocytophilum strains by ankA gene, groEL gene and multilocus sequence typing

Abstract Background Anaplasma phagocytophilum is a Gram-negative Wash and Lotion obligate intracellular bacterium that replicates in neutrophil granulocytes.It is transmitted by ticks of the Ixodes ricinus complex and causes febrile illness called granulocytic anaplasmosis primarily in humans, horses, dogs, sheep, cattle and goats.In comparison, cl

read more



Epigenetic modulations in cancer: predictive biomarkers and potential targets for overcoming the resistance to topoisomerase I inhibitors

AbstractIntroduction Altered epigenetic map is frequently observed in cancer and recent investigations have demonstrated a pertinent role of epigenetic modifications in the response to many anticancer drugs including the DNA damaging agents.Topoisomerase I (Top I) is a well-known nuclear enzyme that is critical for DNA function and cell survival an

read more